Bruce Chesebro Selected Research

Messenger RNA (mRNA)

4/2016

Prion Strain Differences in Accumulation of PrPSc on Neurons and Glia Are Associated with Similar Expression Profiles of Neuroinflammatory Genes: Comparison of Three Prion Strains.

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Bruce Chesebro Research Topics

Disease

35	Prion Diseases (Transmissible Spongiform Encephalopathies) 01/2021 - 03/2002
34	Infections 01/2021 - 03/2002
25	Scrapie 01/2021 - 03/2002
8	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 06/2005
8	Gliosis 01/2020 - 12/2004
7	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 03/2010
6	Brain Diseases (Brain Disorder) 01/2021 - 06/2003
6	Chronic Wasting Disease 01/2019 - 05/2007
6	Neuroinflammatory Diseases 01/2018 - 02/2012
4	Parkinson Disease (Parkinson's Disease) 01/2020 - 09/2015
3	Amyloid Plaque 10/2020 - 06/2005
3	Disease Progression 10/2020 - 01/2016
3	Cerebral Amyloid Angiopathy (Congophilic Angiopathy) 10/2020 - 06/2013
3	Virus Diseases (Viral Diseases) 01/2019 - 06/2004
3	Retinal Degeneration 01/2019 - 12/2004
2	Inflammation (Inflammations) 09/2021 - 02/2012
2	Central Nervous System Diseases (CNS Diseases) 04/2016 - 06/2004
2	Retroviridae Infections (Infection, Retrovirus) 09/2008 - 12/2004
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2021
1	Retinal Diseases 01/2019
1	Bovine Spongiform Encephalopathy (Mad Cow Disease) 01/2019
1	Wounds and Injuries (Trauma) 01/2019
1	Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease) 01/2019
1	Tauopathies 01/2018
1	Hyperlipidemias (Hyperlipidemia) 08/2017
1	Frontotemporal Dementia (Semantic Dementia) 04/2016
1	Seizures (Absence Seizure) 07/2013
1	Viremia 09/2008
1	Dementia (Dementias) 10/2006
1	Multiple Sclerosis 10/2006
1	Heart Diseases (Heart Disease) 07/2006
1	Disease Susceptibility (Diathesis) 01/2003
1	Asymptomatic Infections 12/2002
1	Conversion Disorder (Astasia Abasia) 03/2002

Drug/Important Bio-Agent (IBA)

35	Prion ProteinsIBA 10/2020 - 12/2002
32	PrionsIBA 01/2021 - 06/2005
18	Peptide Hydrolases (Proteases)FDA Link 01/2019 - 03/2002
9	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2003
9	Amyloid (Amyloid Fibrils)IBA 10/2020 - 06/2005
4	PLX5622IBA 09/2021 - 01/2018
4	Retinaldehyde (Retinal)IBA 01/2021 - 12/2004
4	Protein Isoforms (Isoforms)IBA 11/2014 - 03/2002
4	PrPSc ProteinsIBA 12/2004 - 03/2002
3	TEMPOIBA 01/2021 - 10/2012
3	CytokinesIBA 10/2012 - 10/2006
3	ChemokinesIBA 10/2007 - 06/2004
2	RNA (Ribonucleic Acid)IBA 01/2020 - 01/2018
2	Pharmaceutical PreparationsIBA 01/2019 - 01/2018
2	Biological ProductsIBA 07/2013 - 04/2004
2	Membrane Glycoproteins (Membrane Glycoprotein)IBA 07/2013 - 02/2011
2	Glycosylphosphatidylinositols (Glycosyl-Phosphatidylinositol)IBA 02/2011 - 06/2005
1	IntegrinsIBA 01/2020
1	Macrophage Colony-Stimulating Factor Receptor (Receptor, Macrophage Colony Stimulating Factor)IBA 01/2019
1	CausticsIBA 01/2019
1	Sodium Hypochlorite (Clorox)IBA 01/2019
1	Complement C1q (C1q Complement)IBA 01/2018
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018
1	Amino Acids FDA Link 01/2018
1	Toll-Like Receptor 2IBA 01/2018
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 08/2017
1	Simvastatin (Zocor)FDA LinkGeneric 08/2017
1	Pravastatin (Pravachol)FDA LinkGeneric 08/2017
1	Messenger RNA (mRNA)IBA 04/2016
1	Amyloid beta-PeptidesIBA 01/2016
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 02/2015
1	Interleukin-1 Receptors (Interleukin 1 Receptor)IBA 02/2015
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2014
1	Kainic Acid (Kainate)IBA 07/2013
1	Interleukin-12 Subunit p40IBA 10/2012
1	Interleukin-12 Subunit p35IBA 10/2012
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 02/2012
1	Cyclophilin AIBA 02/2012
1	Glycoproteins (Glycoprotein)IBA 06/2009
1	Neutralizing AntibodiesIBA 09/2008
1	Biomarkers (Surrogate Marker)IBA 01/2008
1	Serine (L-Serine)FDA Link 05/2007
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 05/2007
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2004
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 12/2004
1	Chemokine CCL5IBA 12/2004
1	Phosphopyruvate Hydratase (Enolase)IBA 12/2004
1	Glial Fibrillary Acidic ProteinIBA 12/2004
1	Chemokine CXCL10IBA 12/2004
1	LigandsIBA 06/2004
1	VaccinesIBA 08/2002
1	Lymphotoxin-alpha (Lymphotoxin)IBA 05/2002
1	Lymphotoxin-betaIBA 05/2002
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 03/2002
1	PrPC ProteinsIBA 03/2002
1	Phosphoinositide Phospholipase CIBA 03/2002

Therapy/Procedure

2	Euthanasia (Mercy Killing) 01/2018 - 08/2017
1	Drug Therapy (Chemotherapy) 08/2017
1	Transplantation 05/2002